CRONUS-3P for Advanced Nonlinear Microscopy

Laser Source for Advanced Nonlinear Microscopy

High pulse energy for deep imaging
1250 – 1800 nm tuning range for 3P imaging
Down to 50 fs pulse duration for high peak power
Automated wavelength and GDD control for optimal signal
Market-leading pulse-to-pulse energy stability

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CRONUS-3P is a turnkey laser source developed for advanced nonlinear microscopy. It provides µJ-level pulses with durations down to 50 fs at repetition rates of up to 2 MHz. The pulses are tunable in the short-wavelength infrared (SWIR) range from 1250 to 1800 nm, covering the biological transparency windows at 1300 and 1700 nm essential for three-photon (3P) microscopy. Additionally, CRONUS-3P features integrated group delay dispersion (GDD) control, beam steering, and an optional simultaneous 1030 nm output.

Conventional multiphoton imaging in the SWIR range often requires complex multi-device laser systems, large optical tables, and skilled staff, creating barriers for neuroscience and other biomedical applications. CRONUS-3P addresses the challenges as a next‑generation, industrial-grade, single-supplier solution. Compact, reliable, and versatile, it offers tunable femtosecond excitation with GDD compensation to ensure optimal pulse duration at the sample. Its industrial-grade design guarantees high pulse-to-pulse energy and long-term power stability.

Specifications


Model	CRONUS-3P	CRONUS-3P	CRONUS-3P with power control	CRONUS-3P with power control
Model	CRONUS-3P		CRONUS-3P with power control
Output with compressor
Tuning range	1250 – 1800 nm	1250 – 1800 nm	1250 – 1800 nm	1250 – 1800 nm
Tuning range	1250 – 1800 nm
Repetition rate ¹⁾	Single-shot − 1 MHz or 2 MHz	Single-shot − 1 MHz or 2 MHz	Single-shot − 1 MHz or 2 MHz	Single-shot − 1 MHz or 2 MHz
Repetition rate ¹⁾	Single-shot − 1 MHz or 2 MHz
	1300 nm	1700 nm	1300 nm	1700 nm
Pulse duration	< 50 fs	< 65 fs	< 50 fs	< 65 fs
Output power	> 1100 mW @ 1 MHz > 800 mW @ 2 MHz	> 800 mW @ 1 MHz > 500 mW @ 2 MHz	> 1000 mW @ 1 MHz > 700 mW @ 2 MHz	> 700 mW @ 1 MHz > 400 mW @ 2 MHz
GDD control range ²⁾	−4 000 to +9 000 fs²	−12 000 to +3 500 fs²	−4 000 to +9 000 fs²	−12 000 to +3 500 fs²
Beam diameter ³⁾	2 – 4 mm	2 – 4 mm	2 – 4 mm	2 – 4 mm
Beam diameter ³⁾	2 – 4 mm
Beam quality (M²)	< 1.2	< 1.2	< 1.2	< 1.2
Beam quality (M²)	< 1.2
Beam ellipticity	> 0.8	> 0.8	> 0.8	> 0.8
Beam ellipticity	> 0.8
Beam divergence	< 1 mrad	< 1 mrad	< 1 mrad	< 1 mrad
Beam divergence	< 1 mrad
Beam pointing stability	< 100 µrad	< 100 µrad	< 100 µrad	< 100 µrad
Beam pointing stability	< 100 µrad
Long-term power stability, 24 h ⁴⁾	< 1%	< 1%	< 1%	< 1%
Long-term power stability, 24 h ⁴⁾	< 1%
Pulse-to-pulse energy stability, 1 min ⁴⁾	< 1%	< 1%	< 1%	< 1%
Pulse-to-pulse energy stability, 1 min ⁴⁾	< 1%
Main output without GDD control
Output power ⁵⁾	> 1500 mW @ 1 MHz > 1000 mW @ 2 MHz	> 1050 mW @ 1 MHz > 700 mW @ 2 MHz	n/a	n/a
Output power ⁵⁾	> 1500 mW @ 1 MHz > 1000 mW @ 2 MHz	> 1050 mW @ 1 MHz > 700 mW @ 2 MHz	n/a
Auxiliary 1030 nm amplifier output
Center wavelength	1030 ± 10 nm	1030 ± 10 nm	1030 ± 10 nm	1030 ± 10 nm
Center wavelength	1030 ± 10 nm
Maximum output power ⁶⁾	40 W	40 W	40 W	40 W
Maximum output power ⁶⁾	40 W
Maximum repetition rate	2 MHz	2 MHz	2 MHz	2 MHz
Maximum repetition rate	2 MHz
Pulse duration	< 250 fs	< 250 fs	< 250 fs	< 250 fs
Pulse duration	< 250 fs
Optional 680 – 920 nm amplifier output
Center wavelength	680 – 920 nm	680 – 920 nm	680 – 920 nm	680 – 920 nm
Center wavelength	680 – 920 nm
	920 nm	920 nm	920 nm	920 nm
	920 nm
Maximum output power ⁷⁾	> 1500 mW @ 1 MHz > 1000 mW @ 2 MHz	> 1500 mW @ 1 MHz > 1000 mW @ 2 MHz	> 1500 mW @ 1 MHz > 1000 mW @ 2 MHz	> 1500 mW @ 1 MHz > 1000 mW @ 2 MHz
Maximum output power ⁷⁾	> 1500 mW @ 1 MHz > 1000 mW @ 2 MHz
Pulse duration	<290 fs (compressable to <50 fs) ⁸⁾	<290 fs (compressable to <50 fs) ⁸⁾	<290 fs (compressable to <50 fs) ⁸⁾	<290 fs (compressable to <50 fs) ⁸⁾
Pulse duration	<290 fs (compressable to <50 fs) ⁸⁾
Beam quality, M²	< 1.3	< 1.3	< 1.3	< 1.3
Beam quality, M²	< 1.3
Beam diameter ³⁾	1 – 3 mm	1 – 3 mm	1 – 3 mm	1 – 3 mm
Beam diameter ³⁾	1 – 3 mm
Divergence	< 1 mrad	< 1 mrad	< 1 mrad	< 1 mrad
Divergence	< 1 mrad
Long-term power stability, 24 h ⁴⁾	< 1%	< 1%	< 1%	< 1%
Long-term power stability, 24 h ⁴⁾	< 1%
Pulse-to-pulse energy stability, 1 min ⁴⁾	< 1%	< 1%	< 1%	< 1%
Pulse-to-pulse energy stability, 1 min ⁴⁾	< 1%
Optional 1030 nm oscillator output ⁹⁾
Center wavelength	1030 ± 10 nm	1030 ± 10 nm	1030 ± 10 nm	1030 ± 10 nm
Center wavelength	1030 ± 10 nm
Maximum output power	500 mW	500 mW	500 mW	500 mW
Maximum output power	500 mW
Maximum repetition rate	≈ 65 MHz	≈ 65 MHz	≈ 65 MHz	≈ 65 MHz
Maximum repetition rate	≈ 65 MHz
Pulse duration	≈ 200 fs	≈ 200 fs	≈ 200 fs	≈ 200 fs
Pulse duration	≈ 200 fs
Environmental and utility requirements
Operating temperature ¹⁰⁾	19 – 25 ºC (air conditioning recommended)	19 – 25 ºC (air conditioning recommended)	19 – 25 ºC (air conditioning recommended)	19 – 25 ºC (air conditioning recommended)
Operating temperature ¹⁰⁾	19 – 25 ºC (air conditioning recommended)
Relative humidity ¹⁰⁾	20 – 70% (non-condensing)	20 – 70% (non-condensing)	20 – 70% (non-condensing)	20 – 70% (non-condensing)
Relative humidity ¹⁰⁾	20 – 70% (non-condensing)
Laser
Laser
Electrical requirements	100 V AC, 7 A – 240 V AC, 3A; 50 – 60 Hz	100 V AC, 7 A – 240 V AC, 3A; 50 – 60 Hz	100 V AC, 7 A – 240 V AC, 3A; 50 – 60 Hz	100 V AC, 7 A – 240 V AC, 3A; 50 – 60 Hz
Electrical requirements	100 V AC, 7 A – 240 V AC, 3A; 50 – 60 Hz
Rated power	600 W	600 W	600 W	600 W
Rated power	600 W
Power consumption	500 W	500 W	500 W	500 W
Power consumption	500 W
Chiller
Chiller
Electrical requirements	100 – 230 V AC; 50 – 60 Hz	100 – 230 V AC; 50 – 60 Hz	100 – 230 V AC; 50 – 60 Hz	100 – 230 V AC; 50 – 60 Hz
Electrical requirements	100 – 230 V AC; 50 – 60 Hz
Rated power	1400 W	1400 W	1400 W	1400 W
Rated power	1400 W
Power consumption	1000 W	1000 W	1000 W	1000 W
Power consumption	1000 W
Dimensions
Footprint without compressor (L × W) ¹¹⁾	858 × 391 mm (v2) 785 × 350 mm (v1)	858 × 391 mm (v2) 785 × 350 mm (v1)	n/a	n/a
Footprint without compressor (L × W) ¹¹⁾	858 × 391 mm (v2) 785 × 350 mm (v1)		n/a
Footprint with compressor (L × W) ¹¹⁾	858 × 391 mm (v2) 838 × 585 mm (v1)	858 × 391 mm (v2) 838 × 585 mm (v1)	858 × 391 mm (v2)	858 × 391 mm (v2)
Footprint with compressor (L × W) ¹¹⁾	858 × 391 mm (v2) 838 × 585 mm (v1)		858 × 391 mm (v2)


Model	CRONUS-3P	CRONUS-3P	CRONUS-3P with power control	CRONUS-3P with power control
Model	CRONUS-3P		CRONUS-3P with power control

A lower repetition rate with a higher pulse energy option is available.
Continuous dispersion control; −4000 fs² compensates a microscope with +4000 fs².
1/e², measured at compressor output.
Expressed as normalized root mean squared deviation (NRMSD).
Available only for v1. Contact sales@lightcon.com for more details.
Simultaneous up to 1 W. Larger simultaneous output is at the expense of the main output. Contact sales@lightcon.com for more details.
Uncompressed output at 920 nm, no power control.
With an external compressor, < 70% transmission at 920 nm.
Simultaneous to the main output; contact sales@lightcon.com for more details.
Specifications are guaranteed for a maximum temperature variation of ± 1^oC and humidity variation of ± 10%.
See drawings for details.