Three-Channel Wavelength-Tunable Femtosecond Laser CRONUS-2P

  • Watt-level output at high repetition rate for fast imaging
  • Two tunable and one fixed output for simultaneous multibeam excitation
  • Automated GDD control for shortest pulses at the sample
  • Industrial-grade design for high power and beam stability

Features

  • Watt-level output at high repetition rate for fast imaging
  • Two tunable and one fixed output for simultaneous multibeam excitation
  • Automated GDD control for shortest pulses at the sample
  • Industrial-grade design for high power and beam stability

CRONUS-2P is a femtosecond laser providing watt-level three synchronized outputs with high repetition rate, short pulse duration, and GDD control, making it the ultimate source for nonlinear microscopy. In standard configuration, the two independently tunable outputs, operating separately or simultaneously, cover 680 – 960 nm and 960 – 1300 nm, respectively, while the third is fixed at 1025 nm and is accessible in parallel. Thus, the CRONUS-2P can be used for simultaneous excitation of multiple fluorescent probes, calcium indicators, or opsins at their absorption maxima, whereas second- and third‑harmonic emission (SHG and THG) can be spectrally shifted for ease of detection or resonant enhancement.

The two tunable and simultaneous channels also enable advanced coherent anti-Stokes and stimulated Raman scattering (CARS and SRS) applications with dual-band imaging, a broader selection of vibrational resonance frequencies, constant-difference dual‑beam tuning, resonant enhancement, and more.

CRONUS-2P configurations:

  • Standard: 680 – 960 nm (tunable), 960 – 1300 nm (tunable), and 1025 nm (fixed)
  • Dual output A: 680 – 960 nm (tunable), 680 – 960 nm (tunable), and 1025 nm (fixed)
  • Dual output B: 960 – 1300 nm (tunable), 960 – 1300 nm (tunable), and 1025 nm (fixed)
  Output A Output B Output C
Tuning range 1) 680 – 960 nm 960 – 1300 nm 1025 nm (fixed)
Output power 2) > 3 W @ 920 nm > 2.5 W @ 1100 nm > 2.5 W
Pulse duration 3) 4) < 160 fs
Repetition rate 77 ± 1 MHz
Beam quality, M² 3) < 1.2
Polarization Linear, horizontal
Beam divergence, full angle < 1 mrad < 1.5 mrad
Beam diameter 3) (1/e²) 3.0 ± 0.4 mm 3.2 ± 0.4 mm 2.8 ± 0.4 mm
Beam ellipticity 3) > 0.8
Beam astigmatism 3) < 20%
Beam pointing stability 5) < 200 µrad n/a
Long-term power stability 3) 6) < 1%
GDD control range −10000 to −35000 fs² @ 700 nm
−3000 to −20 000 fs² @ 800 nm
0 to −10 000 fs² @ 960 nm
0 to −10 000 fs² @ 960 nm
−3000 to −10 000 fs² @ 1100 nm
−6 000 to −12 000 fs² @ 1300 nm
n/a
  1. Configuration with dual-output A or dual-output B is also available.
  2. Simultaneous mode: > 1 W @ 920 nm, > 1 W @ 1100 nm, and > 2.5 W @ 1025 nm.
  3. Speficied at 920 nm, 1100 nm, and 1025 nm, respectively.
  4. IR pulse duration determined assuming sech2 shape.
  5. Beam pointing deviation over the entire tuning and GDD control range.
  6. Expressed as NRMSD (normalized root mean squared deviation); with less than ±1 °C temperature change after 1 h warm up.
  Output A Output B Output C
Second harmonic tuning range 340 – 480 nm 480 – 650 nm n/a
Conversion efficiency at peak > 30%
  Output A Output B Output C
Altitude < 2000 m
Temperature, operating 18 – 30 °C
Temperature, storage 10 – 35 °C
Relative humidity, operating < 80% (non-condensing)
  Output A Output B Output C
Laser head (L × W × H) 806 × 528 × 311 mm
Rack for power supply and chiller (L × W × H) 642 × 553 × 673 mm

Ketogenic diet uncovers differential metabolic plasticity of brain cells

T. Düking, L. Spieth, S. A. Berghoff, L. Piepkorn, A. M. Schmidke, M. Mitkovski, N. Kannaiyan, L. Hosang, P. Scholz, A. H. Shaib et al., Science Advances 37 (8) (2022).

Exploring two-photon optogenetics beyond 1100~nm for specific and effective all-optical physiology

T. Fu, I. Arnoux, J. Döring, H. Backhaus, H. Watari, I. Stasevicius, W. Fan, and A. Stroh, iScience 3 (24), 102184 (2021).

Label-free imaging of age-related cardiac structural changes in non-human primates using multiphoton nonlinear microscopy

A. Khan, F. Ramos‑Gomes, A. Markus, M. Mietsch, R. Hinkel, and F. Alves, Biomedical Optics Express 11 (12), 7009 (2021).

CRONUS-2P Three-Channel Wavelength-Tunable Femtosecond Laser

Product datasheet.

Rev. 05/01/2023. Size 253.9 KB.

Examples of Microscopy Applications

Application examples.

Rev. 05/01/2023. Size 1.8 MB.

Laser Sources for Nonlinear Microscopy

Broshure.

Rev. 15/01/2023. Size 4.1 MB.

Femtosecond Laser Systems for Science

Product catalog.

Rev. 15/01/2023. Size 16.1 MB.

飞秒激光器飞秒科研系统

Product catalog in Chinese.

Rev. 29/12/2022. Size 14.7 MB.